牛海月

发布者:生命健康学院发布时间:2025-03-25浏览次数:10


姓名:牛海月

博士

单位:生命健康学院 生物工程系

办公地址:湖州学院1-5B01

研究方向:益生菌作用机制与精准健康干预;发酵食品微生物资源开发与功能挖掘;微生物代谢互作与生态调控

办公电话:-

电子邮箱:niuhaiyue@zjhzu.edu.cn

个人简介:

牛海月,女,1993年生,博士,助理研究员。20226月获哈尔滨工业大学化学工程与技术专业工学博士学位,同年8月进入浙江省农业科学研究院开展博士后研究(至20248月),202410月起任职于湖州学院生命健康学院。长期致力于功能益生菌作用机制与精准健康干预、发酵食品微生物组学与代谢调控等领域的教学与科研工作,重点研究方向包括:母婴微生态健康调控菌株开发、发酵体系微生物互作及代谢产物解析等。作为核心成员参与省部级科研项目及横向课题2项,累计发表SCI学术论文13篇,获授权国家发明专利2项(抗腹泻功能菌株方向)、实用新型专利2项(食品发酵设备优化方向)。

教学与课程:

 1.《发酵工程》

 2.《食品营养与保健》

 3.《化妆品赏析与应用》

科研项目、成果:

(一)科研项目:

 (1) 粉本农业科技(湖州南浔)有限公司, 企业横向, 2023R15F001, 生物抑菌技术及料理食品开发, 2023-01 至今, 60万元, 在研, 参与

 (2) 浙江省农业农村厅, 浙江省“三农九方”科技协作计划“揭榜挂帅”项目, 2023SNJF017, 浙江特色柑橘益生菌发酵型全果汁风味特征解析及加工关键技术研究, 2023-01至今, 50万元, 在研, 参与

(二)论文

 1. Haiyue Niu; Jianming Zhang; Chengcheng Zhang; Xiaoting Xin; Daqun Liu; Halophilic microbes and mineral compositions in salts associated to fermentation and quality of fermented radish, LWT-Food Science and Technology, 2024, (193): 115746SCI 收录,中科院一区TopIF5=6

 2. Haiyue Niu; Xiaohong Zhou; Ping Liu; Yifan Wu; Linzheng Lyu; Tongjie Liu; Zhe Zhang;Jiliang Zhang; Shiwei Chen; Pimin Gong; Xue Han; Lanwei Zhang; Lactobacillus rhamnosus MN-431 metabolic tryptophan alleviates complementary food-induced diarrhea through PXR–NF-κB pathway and AHR–Th17 cell response pathways, Molecular Nutrition & Food Research, 2023, 67(13):2200530SCI 收录,中科院二区,IF5=5.6

 3. Haiyue Niu; Xiaohong Zhou; Xuguang Zhang; Tongjie Liu; Yifan Wu; Linzheng Lyu; Cong Liang; Shiwei Chen; Pimin Gong; Jiliang Zhang; Xue Han; Shilong Jiang; Lanwei Zhang; Breast milk contains probiotics with anti-infantile diarrhoea effects that may protect infants as they change to solid foods, Environmental Microbiology, 2021, 23(3): 1750 1764SCI 收录,中科院二区,IF5=5.2

 4. Haiyue Niu; Xiaohong Zhou; Pimin Gong; Yuehua Jiao; Jiliang Zhang; Yifan Wu; Linzheng Lyu; Cong Liang; Shiwei Chen; Xue Han; Lanwei Zhang; Effect of Lactobacillus rhamnosus MN-431 Producing Indole Derivatives on Complementary Feeding-Induced Diarrhea Rat Pups Through the Enhancement of the Intestinal Barrier Function, Molecular Nutrition & Food Research, 2021, 66(2):2100619SCI 收录,中科院二区,IF5=5.6

 5. Haiyue Niu; Jianming Zhang; Chengcheng Zhang; Xiaoting Xin; Daqun Liu; Unraveling the metabolite profiles and microbial roles during dry-pickled radish fermentation, Journal of Food Measurement and Characterization, 2025, 19(2): 1022-1036SCI 收录,中科院三区,IF5=3.0

 6.Cong Liang, Haiyue Niu,Linzheng Lyu, et al., Profiles of Intestinal Flora in Breastfed Obese Children and Selecting Functional Strains Against Obesity,Molecular Nutrition & Food Research, 2024, 68(4): 2300735.SCI 收录,中科院二区,IF5=5.6

 7. Shiwei Chen, Haiyue Niu, Yiwan Wu, Jialei Sun, Xue Han, Lanwei Zhang. Influence of Lactic Acid on Cell Cycle Progressions in Lactobacillus bulgaricus During Batch Culture. Appl Biochem Biotechnol. 2021, 193(3):912-924SCI 收录,中科院三区,IF5=2.9

 8. Shiwei Chen, Yiwan Wu, Haiyue Niu, Jialei Sun, Xue Han, Lanwei Zhang. Imbalance between peptidoglycan synthases and hydrolases regulated lysis of Lactobacillus bulgaricus in batch culture. Arch Microbiol. 2021, 203(7):4571-4578SCI 收录,中科院三区,IF5=2.6

 9. ChengchengZhang, Jianming Zhang, Xiaoting Xin, Haiyue Niu, Xiaojun Liao, Daqun Liu. Reduced formation of biogenic amines in low-salt Zhacai via fermentation under CO2-modified atmosphere. Food Res Int. 2023, 163:112256. SCI 收录,中科院一区TOPIF5=7.4

 10. Jialei Sun, Wenjing Cai, Yu Wang, Haiyue Niu, Xi Chen, Xue Han. The Effect of Decreased Ca++/Mg++ ATPase Activity on Lactobacillus delbrueckii subsp. bulgaricus sp1.1 Survival during Spray Drying. Foods. 2023 Feb 13;12(4):787. SCI 收录,中科院二区,IF5=5.1

 11. Jianming Zhang, Daiyao Liu, Chengcheng Zhang, Haiyue Niu, Xiaoting Xin, Juan Chen, Huaxi Yi, Daqun Liu. The impact of Levilactobacillus brevis YSJ3 and Lactiplantibacillus plantarum JLSC2-6 co-culture on gamma-aminobutyric acid yield, volatile and non-volatile metabolites, antioxidant activity, and bacterial community in fermented cauliflower byproducts. Food Chem. 2024, 432:137169.SCI 收录,中科院一区TOPIF5=8.3

 12. Hui Liu, Daiyao Liu, Chengcheng Zhang, Haiyue Niu, Xiaoting Xin, Huaxi Yi, Daqun Liu, Jianming Zhang. Whole-genome analysis, evaluation and regulation of in vitro and in vivo GABA production from Levilactobacillus brevis YSJ3. Int J Food Microbiol. 2024, 421:110787. SCI 收录,中科院一区TOPIF5=5.0

 13. Qinghang Wu, Daqun Liu, Jianming Zhang, Ting Li, Haiyue Niu, Xiaoting Xin, Shengming Zhao, Chengyun He, Chengcheng Zhang. Enhancing the formation of functional glucosinolate degradation products in fermented broccoli stalk by-product with lactic acid bacteria. Food Chem. 2025, 464(Pt 1):141689. SCI 收录,中科院一区TOPIF5=8.3

(三)授权专利

发明专利:

 1.一种防止婴儿因补充辅食引起腹泻的菌株及其应用,ZL202110852169.X(已授权)

 2.一株干酪乳杆菌FN345及其在制备预防辅食期婴儿腹泻菌剂中的应用,ZL202210350639.7(已授权)

 3.一种包载量子点和植物乳杆菌的抗菌抗氧化水凝胶球及其制备方法,CN202310917762.7(实质审查)

 4.一种鸡粪强力降解菌剂及其在制备青虾饲料中的应用,CN202310420884.5(实质审查)

 5.一种牛粪腐熟菌剂及其制备方法和应用,CN202310420905.3(实质审查)

 6.一种猪粪强力降解菌剂及其制备方法和应用,CN202310420897.2(实质审查)

 7.一种立体式稳定循环水养殖青虾的系统与方法,CN202211571929.0(实质审查)

实用新型专利:

 8. 一种乳酸菌发酵罐,CN202321784715.1(已授权)

 9.一种气体监测的蔬菜发酵罐,CN202321535510.X (已授权)