李梅

教师基本情况

教育作经历

1999-2003，三峡大学化学教育专业，获学士学位；
2003-2006，广西师范大学化学化工学院无机化学专业，获硕士学位；
2011-2014，中南大学化学化工学院应用化学专业，获博士学位；

工作经历

2020年7月进入湖州学院生命健康学院工作

课程教学

目前承担药物化学及实验、药物合成反应及实验、制药有机化学等本科生课程的教学。

教研及科研项目

主要成果

1. Li M, Xu X, Cai QY. DNA polymerase/NEase-assisted signal amplification coupled with silver nanoclusters for simultaneous detection of multiple microRNAs and molecular logic operations. Sensors and Actuators: B. Chemical. 2021, 327 (2021) 128915.

2. Li M, Xu X, Zhou ZG, Xu GH, Xie YR, Cai QY. Label-free detection of microRNA: two-stage signal enhancement with hairpin assisted cascade isothermal amplification and light-up DNA-silver nanoclusters. Microchimica Acta. 2020, 187:141.

3. Li M, Xu X, Cai QY, Luo XJ, Zhou ZG, Xu GH, Xie YR. Graphene oxide-based fluorometric determination of microRNA-141 using rolling circle amplification and exonuclease III-aided recycling amplification. Microchimica Acta. 2019, 186:531.

4. Li M, Huang S, Cai Q, Xie Y. Spectroscopic investigation and in vitro cytotoxic activity toward HepG2 cells of a copper compound complexed with human serum albumin. Luminescence. 2017, 32(5):888-898. 

5. Li M, Huang S, Ye C, Xie Y. Synthesis,structure,protein binding of Cu(II) complexes with a tridentate NNO Schiff-base ligand. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy. 2015, 150:290-300.

6. Li M, Lee P, Zhang Y, Ma Z, Yang F, Zhou Z, Wu X, Liang H. X-ray Crystallographic and Fluorometric Analysis of the Interactions of Rhein to Human Serum Albumin. Chemical Biology & Drug Design. 2014, 83(2):167-173.

7. Li M, Kong LL, Gou Y, Yang F, Liang H. Synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity of a mixed-ligand copper(II) complex with taurine Schiff base and imidazole. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy. 2014, 128C:686-693.

8. Li M, Gou Y, Yang F, Liang H. Synthesis, structure, protein binding and cytotoxicity of zinc(II) complexes with tridentate NNO Schiff-base ligands. Journal of Coordination Chemistry. 2014, 67(6):929-942.

9. Li M, McAuley E, Zhang Y, Kong L, Yang F, Zhou Z, Wu X, Liang H. Comparison of binding characterization of two antiviral drugs to Human Serum Albumin. Chemical Biology & Drug Design. 2013, 83(5):576-582.