| 姓名：潘海峰 | 博士/高级工程师 |
单位：生命健康学院 | 办公地址：湖州学院理学院教学楼1号楼 | |
研究方向：合成生物学、生物催化与转化、酶学、生物质资源利用 | 办公电话：13588881534 | |
电子邮箱： panhaifeng@zjhzu.edu.cn | ||
个人简介： 潘海峰，男，1984年生，博士，高级工程师。2011年06月毕业于浙江大学生化与分子生物学专业，获博士学位；2013年07月从浙江大学大学药学博士后流动站出站，进入杭州宝晶生物股份有限公司工作。 现为湖州学院生命健康学院专任教师，入选浙江省151人才计划。主要从事合成生物学、生物转化与催化、生物资源利用等相关的教学和科研工作，主持国家自然科学基金1项、主持国家博士后基金资助1项、参与国家863计划1项、省部级项目3项，完成企业技术项目20余项，发表学术论文20余篇，其中SCI、EI检索10余篇，获授权国家发明专利15项。 | ||
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育人成果：
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科研项目、成果： 文章： [1] Wenna Bao, Adel Almarashi, Haifeng Pan, Yongqiang Du, Alibek Issakhov, Xuan Vuong Bui, Shaowen Yao, Anh Tien Nguyen. Hybrid nanomaterial transportation and Lorentz effects in a permeable sinusoidal duct. Journal of Molecular Liquids（2区、IF6.165）,2021, 332:115796. [2] 陈曦，鲍文娜，黄美娟，李怡辉，潘海峰，谢志鹏，张建国. 出芽短梗霉产聚苹果酸发酵条件的优化. 微生物学通报，2018,45 (2): 231-237. [3] 姚伶俐, 潘海峰, 田文娟, 惠天聪, 谢志鹏, 张建国. 代谢工程改造大肠杆菌合成丁二酸及发酵罐放大工艺,微生物学通报，2018,45(12):2541-2551. [4] Haifeng Pan, Zhipeng Xie, Wenna Bao, Yongqing Cheng, Jianguo Zhang, Yongquan Li. Site-directed mutagenesis of epoxide hydrolase to probe catalytic amino acid residues and reaction mechanism, FEBS Letters（3区、IF 3.582）, 2011, 585(15):2545-2550. [5] Haifeng Pan, Wenna Bao, Zhipeng Xie, Jianguo Zhang* and Yongquan Li. Molecular cloning and characterization of a cis-epoxysuccinate hydrolase from Bordetella sp. BK-52, Journal of Microbiology and Biotechnology（4区、2.351）, 2010, 20(4): 659-665. [6] Haifeng Pan, Wenna Bao, Zhipeng Xie, Jianguo Zhang. Optimization of medium composition for cis-epoxysuccinate hydrolase production in Escherichia coli by response surface methodology, African Journal of Biotechnology, 2010, 9(9): 1366-1373. [7] Haifeng Pan, Wenna Bao, Zhipeng Xie, Jianguo Zhang, Yongquan Li. Immobilization of Escherichia coli cells with cis-epoxysuccinate hydrolase for D(-)-tartaric acid production, Biotechnology Letters（4区、2.461）, 2010, 32(2): 235-241. [8] Haifeng Pan, Zhipeng Xie, Wenna Bao, Jianguo Zhang. Optimization of culture conditions to enhance cis-epoxysuccinate hydrolase production in Escherichia coli by response surface methodology. Biochemical Engineering Journal（3区、3.978）, 2008, 42(2):133-138. [9] Haifeng Pan, Zhipeng Xie, Wenna Bao, Jianguo Zhang. Isolation and identification of a novel cis-epoxysuccinate hydrolase-producing Bordetella sp. BK-52 and optimization of enzyme production, Acta Microbiologica Sinica, 2008, 48(8): 1075-1081. [10] Changling Zhang, Haifeng Pan, Lingli Yao, Wenna Bao, Jinxin Wang, Zhipeng Xie, Jianguo Zhang. Single point mutations enhance activity of cis-epoxysuccinate hydrolase. Biotechnology Letters（4区、2.461）, 2016, 38:1301-1306. [11] Wenna Bao, Haifeng Pan, Zhenhong Zhang, Yongqing Cheng, Zhipeng Xie, Jianguo Zhang. Isolation of the stable strain Labrys sp. BK-8 for L(+)-tartaric acid production. Appl J Biosci Bioeng（3区、2.894）, 2015, 119(5): 538-542. [12] Wenna Bao, Haifeng Pan, Zhenhong Zhang, Yongqing Cheng, Zhipeng Xie, Jianguo Zhang, Yongquan Li. Analysis of essential amino acid residues for catalytic activity of cis-epoxysuccinate hydrolase from Bordetella sp. BK-52. Applied Microbiology and Biotechnology（2区、4.813）, 2014, 98(4):1641-1649. [13] Yongqing Cheng, Haifeng Pan, Wenna Bao, Weirong Sun, Zhipeng Xie, Jianguo Zhang, Yuhua Zhao. Cloning, homology modeling, and reaction mechanism analysis of a novel cis-epoxysuccinate hydrolase from Klebsiella sp. Biotechnology Letters（4区、2.461）, 2014, 36(11):2325-2330. [14] Yongqing Cheng, Li Wang, Haifeng Pan, Wenna Bao, Weirong Sun, Zhipeng Xie, Jianguo Zhang, Yuhua Zhao. Purification and characterization of a novel cis-epoxysuccinate hydrolase from Klebsiella sp. that produces L(+)-tartaric acid. Biotechnology Letters（4区、2.461）, 2014, 36(11):2325-2330. [15] Wenna Bao, Haifeng Pan, Min Lu, Yuan Ni, Rui Zhang, Xingguo Gong. The apoptosis effect of Sarsasapogenin from Anemarrhena asphodeloides on HepG2 human hepatoma cells. Cell Biology International（3区、3.612）, 2007, 31: 887-892. [16] Yanqing Lin, Zhipeng Xie, Jianguo Zhang, Wenna Bao, Haifeng Pan, Boyi Li. Cloning and characterization of a novel NAD+-dependent xylitol dehydrogenase from Gluconobacter oxydans CGMCC 1.637. Acta microbiologica sinica, 2012, 52(6):726-735. [17] 兰翔，鲍文娜，潘海峰，谢志鹏，张建国. 根瘤菌BK-20固定化细胞生成L(+)-酒石酸. 生物工程学报，2014,30(2): 315-319. [18] 李博义，潘海峰，孙伟荣，程永青，谢志鹏，张建国. 5-酮基-D-葡萄糖酸发酵生产的工艺条件优化. 生物工程学报，2014,30(8): 1-5. [19] 李永泉，谢志鹏，潘海峰，叶兴乾，张建国. L-酒石酸高效生物合成技术及产业化. 中国食品科学技术学会年会，2014，212. | ||
社会服务： 1、担任湖州2021年南太湖精英计划创业A类项目企业的首席科学家和技术顾问 2、担任杭州生物研发企业的首席顾问
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